7,005 research outputs found

    Paid Sick Days Access in the United States: Differences by Race/Ethnicity, Occupation, Earnings, and Work Schedule

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    Paid sick days bring substantial benefits to employers, workers, families, and communities. The economic and public health benefits of paid sick leave coverage include safer work environments; improved work life balance, reduced spread of contagion; and reduced health care costs. Access to this important benefit, however, is still too rare, and is unequally distributed across the U.S. population, with differences by race and ethnicity, occupation, earnings levels, and work schedules. Utilizing data from the National Health Interview Survey (NHIS), IWPR finds that in 2012, approximately 61 percent of private-sector workers age 18 and older in the U.S. had access to paid sick days (Figure 1); up from 57 percent in 2009. More than 41 million workers lack access

    Talk it up! — Integrating and prioritizing conversational data in documentation

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    Syllabus for workshop, CoLang 2016This course will introduce participants to some of the basic methodological and theoretical issues related to recording and analyzing everyday conversations. We will discuss specific contributions of naturalistic interactions to understanding aspects of linguistic structure, social interaction, and culture and explore how interactional data can be better integrated into language documentation projects.2015 NSF/BCS 1500841: CoLang 2016: Institute on Collaborative Language Research – ALASKA Alaska Native Language Cente

    Interview with Chris Wallace-Crabbe

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    Evaluating Engineering Reference eBooks

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    Co-receptor CD8-mediated modulation of T-cell receptor functional sensitivity and epitope recognition degeneracy

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    The interaction between T-cell receptors (TCRs) and peptide epitopes is highly degenerate: a TCR is capable of interacting productively with a wide range of different peptide ligands, involving not only cross-reactivity proper (similar epitopes elicit strong responses), but also polyspecificity (ligands with distinct physicochemical properties are capable of interacting with the TCR). Degeneracy does not gainsay the fact that TCR recognition is fundamentally specific: for the vast majority of ligands, the functional sensitivity of a given TCR is virtually null whereas this TCR has an appreciable functional sensitivity only for a minute fraction of all possible ligands. Degeneracy can be described mathematically as the probability that the functional sensitivity, of a given TCR to a randomly selected ligand, exceeds a set value. Variation of this value generates a statistical distribution that characterizes TCR degeneracy. This distribution can be modeled on the basis of a Gaussian distribution for the TCR/ligand dissociation energy. The kinetics of the TCR and the MHCI molecule can be used to transform this underlying Gaussian distribution into the observed distribution of functional sensitivity values. In the present paper, the model is extended by accounting explicitly for the kinetics of the interaction between the co-receptor and the MHCI molecule. We show that T-cells can modulate the level of degeneracy by varying the density of co-receptors on the cell surface. This could allow for an analog of avidity maturation during incipient T-cell responses

    Aerospace Section

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    The Aerospace Section of the Engineering Division encourages communication and cooperation among information professionals concerned with aerospace, aeronautical and related technologies. In addition, it fosters dialog with entities such as NASA, the AIAA and other important sources of technical data and bibliographical services

    Age-related shifts in bacterial diversity in a reef coral

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    This study investigated the relationship between microbial communities in differently sized colonies of the massive coral Coelastrea aspera at Phuket, Thailand where colony size could be used as a proxy for age. Results indicated significant differences between the bacterial diversity (ANOSIM, R = 0.76, p = 0.001) of differently sized colonies from the same intertidal reef habitat. Juvenile and small colonies (28 cm mean diam). Bacterial diversity increased in a step-wise pattern from juvenilessmallmedium colonies, which was then followed by a slight decrease in the two largest size classes. These changes appear to resemble a successional process which occurs over time, similar to that observed in the ageing human gut. Furthermore, the dominant bacterial ribotypes present in the tissues of medium and large sized colonies of C. aspera, (such as Halomicronema, an Oscillospira and an unidentified cyanobacterium) were also the dominant ribotypes found within the endolithic algal band of the coral skeleton; a result providing some support for the hypothesis that the endolithic algae of corals may directly influence the bacterial community present in coral tissues.Barbara Brown recieved funding from the Leverhulme Trust [www.leverhulme.ac.uk]; Grant number: EM-2013-058. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

    Annual Survey of Virginia Law: Charitable Immunity: What Price Hath Charity?

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    It is well settled in Virginia that charitable organizations are immune from liability arising from tort claims asserted by persons who accept the organizations\u27 charitable benefits. The determination of whether a plaintiff is the beneficiary of charitable bounty is a legal issue for the court to decide. Although most older Virginia cases discuss charitable immunity as it applies to hospitals, the doctrine has been applied to many other types of charitable organizations
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